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Thank you once again.

My pet- phrase at work & of late on-line is 'context' which you consistently do. 🙂

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author

I couldn’t agree more. Context is incredibly important, no matter WHAT you’re talking about!

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Dr. Andrea

I would appreciate an explanation or possibly a link to an article that speaks to the lack of longer term immunity to influenzae & coronavirus infectiouns.

I do appreciate & each share ability to "recreate" themselves via new variants.

I would also expect neither stimulate a cellular response.

I'm also a bit perplex with the "recommendation" not to repeat CoVid-19 "booster" doses within 6 mo's.

Possibly you occasionally read Dr. Ryan McCormick posts. I copied the following from his recent chat about influenzae.

How long does the flu shot provide protection?

Some protection is durable, but the highest protection is in the first month or two.

Flu vaccine effectiveness wanes 9% q 28 days, starting 41 days post-vaccination in adults (but not in children, who were found to have stable protection throughout the whole season!), according to a study published this year in Eurosurveillance. The study went out to 5 months after flu vaccination and found that overall:

Our results were comparable with other studies examining protection by time since influenza vaccination. A study from Singapore (which has year-round influenza activity due to its tropical climate) found that the infection odds increased 1.07 times every 8 weeks since vaccination.

A study in the US found that the odds of influenza A(H3N2) infection increased 1.12 times every 14 days.

Another US study found that the odds of influenza increased 1.16 times q 28 days.

Ref: Substack Dr. Ryan McCormick Aug/24

Maybe TMI...I was fascinated to read early into the COVID pandemic about residents (possibly New Jersey) in a seniors facility who were 90+ yr and s nun ~ 100 yr's that recovered from the particularly nasty original variant. In addition to being "tough old birds" could or did they have the advantages of decades of exposure to more "ancient" variants of the coronaviruses and as such some cross-protection? If this were to be true then my conclusion is there not some cellular immunity.

Appreciatively, John

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