Can you address research suggesting that glyphosate has an adverse effect on the GI tract via the microbiome? I see that there's a paragraph on that issue in the linked article -- but there, you suggest that the only studies are in vitro, and that the "trace levels" are too low to have an adverse effect anyway. But it appears there are studies that are not merely in vitro studies, and that have attempted to deal with the dosage issue. Here's one: https://www.sciencedirect.com/science/article/abs/pii/S1382668923000911. From the abstract, they say: "[using] fecal samples from C57BL/6 J mice, we show that glyphosate exposure at doses approximating the U.S. ADI significantly impacts gut microbiota composition. These gut microbial alterations were associated with effects on gut homeostasis characterized by increased proinflammatory CD4+IL17A+ T cells and Lipocalin-2, a known marker of intestinal inflammation." So, the authors are tying to take into account the issue of dosage. Can you address this? (Many people have functional GI issues, with no known structural cause -- so you can understand if they'd want to cut down on anything that might exacerbate inflammation.)
Thanks for your comment, Mark! I recommend reading through the piece I wrote about glyphosate and Celiac as well as my gluten piece - I think that will answer those questions.
OK, follow up, I found that post. I see that you make points about correlation not necessarily equaling causation, etc. - but I don't see anything there about research on glyphosate (and other pesticides) as possible causes of GI inflammation. Can you address that research? (And whether you think it's flawed -- and if so, why?)
You’re on fire, girl!! 🙌🏼
I have to admit, half of the motivation was to ensure people read our Skeptical Inquirer feature article, but I think this rounded out the story well!
Can you address research suggesting that glyphosate has an adverse effect on the GI tract via the microbiome? I see that there's a paragraph on that issue in the linked article -- but there, you suggest that the only studies are in vitro, and that the "trace levels" are too low to have an adverse effect anyway. But it appears there are studies that are not merely in vitro studies, and that have attempted to deal with the dosage issue. Here's one: https://www.sciencedirect.com/science/article/abs/pii/S1382668923000911. From the abstract, they say: "[using] fecal samples from C57BL/6 J mice, we show that glyphosate exposure at doses approximating the U.S. ADI significantly impacts gut microbiota composition. These gut microbial alterations were associated with effects on gut homeostasis characterized by increased proinflammatory CD4+IL17A+ T cells and Lipocalin-2, a known marker of intestinal inflammation." So, the authors are tying to take into account the issue of dosage. Can you address this? (Many people have functional GI issues, with no known structural cause -- so you can understand if they'd want to cut down on anything that might exacerbate inflammation.)
Thanks for your comment, Mark! I recommend reading through the piece I wrote about glyphosate and Celiac as well as my gluten piece - I think that will answer those questions.
OK, follow up, I found that post. I see that you make points about correlation not necessarily equaling causation, etc. - but I don't see anything there about research on glyphosate (and other pesticides) as possible causes of GI inflammation. Can you address that research? (And whether you think it's flawed -- and if so, why?)
You mean a piece apart from this post, and apart from the Skeptical Inquirer piece? I don't see that. Can you link to it? Thank you.